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Atrial Fibrillation From Bench to Bedside Book

The prevalence of atrial fibrillation (AF) is increasing worldwide, resulting in a cardiovascular “epidemic.” The rise in the prevalence of AF can be predominantly attributed to aging of the population and a higher incidence of cardiovascular diseases. The reasons for the increase in prevalence of AF has yet to be completely elucidated; age, gender, race, and cardiovascular disease have been shown to correlate with AF prevalence. It is estimated that AF affects 2.2 million individuals in the United States. However, the prevalence of AF may be underestimated because of a large number of asymptomatic individuals. It is projected that the aging of the population will result in 2.5-fold rise in the prevalence of AF by 2050. When considering both the aging of the population and the prevalence of AF, preventive measures that reduce the incidence of AF will have substantial economic and societal benefits.

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